Why the study?
Do oral atenolol and propranolol alter ventilation and respiratory gas exchange during exercise in healthy untrained subjects compared to placebo?
Population
6 healthy but untrained subjects
Comparison
Oral doses of the beta 1-selective adrenoceptor… vs Placebo
Authors
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May warrant caution with beta-blockers in active individuals; leaves open effects in patients with cardiopulmonary disease.
Do oral atenolol and propranolol alter ventilation and respiratory gas exchange during exercise in healthy untrained subjects compared to placebo?
Both beta 1-selective and non-selective beta-blockers significantly reduce peak expiratory flow and tidal volume during exercise in healthy subjects, which is compensated by an increased respiratory rate.
McLeod et al. (1985) studied this question.
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