Why the study?
When patients do not present to a 24/7 PCI-capable facility, delays can exceed the recommended 90 minutes; this study evaluated the impact of inter-hospital transfers on performance indices in STEMI.
Does inter-hospital transfer increase time to treatment in STEMI patients compared to direct presentation?
Does inter-hospital transfer increase time to treatment in STEMI patients compared to direct presentation?
Inter-hospital transfer for STEMI significantly increases total ischemic time compared to direct presentation, despite similar door-to-balloon times at the receiving PCI-capable hospital.
Answers are grounded in this paper and cite their sources.
May increase ischemic burden in transferred STEMI patients; leaves open the need for outcome-focused trials on triage optimization.
BACKGROUND: Key performance indices such as door-to-balloon times have long been recognized as quality metrics in reducing time to care for patients with acute coronary syndromes (ACS). In the situation where patients do not present to a facility capable of 24/7 percutaneous coronary interventions (PCI) delays in time to therapy can exceed the recommendation of 90 min or less. This study aimed to evaluate the impact of transfers on performance indices for patients diagnosed with ST-segment elevation myocardial infarction (STEMI). METHODS: Over a seven month collection period, all patients presenting with symptoms suggestive of ACS and admitted for PCI were studied. Patients were divided into dichotomous groups of direct presentations or transfers from a secondary non-PCI capable hospital with key times recorded, including symptom-onset, first hospital and PCI-capable hospital arrival and balloon inflation times to evaluate time of treatment for STEMI patients. RESULTS: = 19) did within 120 min, although all received balloon inflation within 90 min from arrival at the PCI-H. After controlling for confounding factors of socio-economic status, presentation date/time and diagnostic category, transferred patients experienced an average 162% longer delays from symptom-onset to PCI-H door arrival, and 98% longer delays in symptom-onset to balloon inflation; compared to patients who present directly to the PCI-H. No statistically significant differences were noted between transferred and direct patients when measured from PCI-H door-to-balloon times. CONCLUSIONS: This study shows that transferred patients experience a greater overall system delay, compared to patients who present directly for PCI, significantly increasing their time to treatment and therefore infarct times. Despite the majority of transfers experiencing pre-hospital activation, their treatment hospital arrival to balloon times are no less than direct presenters after controlling for confounding factors, further compounding the overall delay to therapy.
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Forsyth et al. (2020) studied this question.
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