Why the study?
Percutaneous transcatheter valve repair can cause hemodynamic instability and an elevated burden of intraoperative hypotension, prompting the need to evaluate machine learning-guided hemodynamic management.
Does HPI-based hemodynamic guidance reduce intraoperative hypotension in patients undergoing percutaneous transcatheter valve repair?
Population
69 patients undergoing PTVR
Comparison
Proactive treatment protocol when Hypotension Prediction Index exceeded 85
Design
Prospective observational study
Follow-up
Average monitoring time of 191.61 ± 52 minutes per patient
Key result
Hemodynamic guidance using the Hypotension Prediction Index during transcatheter valve repair resulted in a median time-weighted average mean arterial pressure <65 mmHg of 0.17 mmHg.
Authors
Loading...
HPI guidance may attenuate IOH burden during PTVR; leaves open outcome benefit in randomized trials.
Observational (n=69)
Does HPI-based hemodynamic guidance reduce intraoperative hypotension in patients undergoing percutaneous transcatheter valve repair?
Application of an HPI-based hemodynamic guidance algorithm during percutaneous transcatheter valve repair limits the incidence and severity of intraoperative hypotension.
Lombardi et al. (2026) conducted an observational in Percutaneous transcatheter valve repair (n=69). Hypotension Prediction Index (HPI) based hemodynamic guidance was evaluated on Time weighted average (TWA) mean arterial pressure (MAP) under 65 mmHg threshold. Hemodynamic guidance using the Hypotension Prediction Index during transcatheter valve repair resulted in a median time-weighted average mean arterial pressure <65 mmHg of 0.17 mmHg.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: