Why the study?
Does intraoperative hypotension increase the risk of postoperative acute kidney injury in patients undergoing elective noncardiac surgery?
Does intraoperative hypotension increase the risk of postoperative acute kidney injury in patients undergoing elective noncardiac surgery?
This study aims to determine the minimum magnitude and duration of intraoperative hypotension needed to trigger postoperative acute kidney injury.
Intraoperative hypotension thresholds for postoperative AKI remain undefined; leaves open precise magnitude/duration criteria in noncardiac surgery.
(Abstracted from Anesthesiology, 123:515–523, 2015) In the literature, intraoperative hypotension (IOH) has been defined as systolic blood pressure (BP) less than 80 mm Hg, a mean arterial pressure (MAP) less than 50 to 60 mm Hg, and decrease in either of 25% from baseline. However, despite IOH being an important determinant of postoperative acute kidney injury (AKI), no clear evidence has determined the minimum magnitude and duration of hypotension needed to trigger harm.
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Sun et al. (2016) studied this question.
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