Reports a novel case of reversible vacuolar myopathy of type II fibers with associated bradycardia and T wave changes that resolved spontaneously.
Spontaneous resolution may support conservative management in similar cases; leaves open the natural history of reversible type II vacuolar myopathy.
A 23-year-old ex-bicycle racer with vague gastrointestinal symptoms had an acute weight loss of 13.6 kg (30 lb). During the period of maximal weight loss, he experienced muscle weakness, dysphagia, bradycardia, and T wave changes on the electrocardiogram. His skeletal muscle biopsy showed a severe vacuolar myopathy devastating the atrophic type II fibers. Without treatment, he recovered completely and has remained well. This may be an exaggerated or acute form of type II atrophy not previously reported, or it may represent an acute muscular degeneration.
No takes yet. Share an insight, caveat, or question.
Hanson et al. (1975) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: