December 1, 1978Archives of Neurology

Muscle Fiber-Type Disproportion

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Population

4 members of a family

Design

Case_series

Authors

TEToomas EislerNational Institute of Mental Health

Discussion

Member takes

Implication

Hypothesis-generating for novel type I fiber predominance myopathy; larger studies needed before diagnostic or prognostic implications.

Structured PICO

Population

4 members of a family (2 symptomatic with slowly progressing proximal muscle weakness starting from ages 2 and 6 years, and 2 asymptomatic members)

Outcome

Muscle biopsy findings (predominance of type I fibers and minimally enlarged type II fibers)surrogate

Describes a novel syndrome of type I muscle fiber predominance presenting with proximal muscle weakness or asymptomatic elevation of creatine phosphokinase.

Cite This Study

Toomas Eisler (1978) studied this question.

synapsesocial.com/papers/6a897cab755d28965dfd4735 https://doi.org/10.1001/archneur.1978.00500360047009

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Muscle Fiber-Type Disproportion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Muscle Fiber-Type Disproportion

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider