Why the study?
Do inotropic interventions alter the rate of change of ventricular diastolic dimensions in open-chest dogs?
Do inotropic interventions alter the rate of change of ventricular diastolic dimensions in open-chest dogs?
Inotropic interventions alter systolic contraction but do not have a concomitant effect on early diastolic relaxation in a canine model.
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Inotropic stimulation enhances systolic wall thickening without altering early diastolic thinning in dogs; leaves open translation to human diastolic assessment.
Sabbah et al. (1981) studied this question.
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