Population
Sheep and goats infected with naturally occurring nononcogenic retroviruses (lentiviruses)
Design
Review
Authors
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May inform macrophage-targeted strategies in animal lentiviruses; leaves open translation to human disease.
This review outlines the pathogenesis of lentiviral diseases in sheep and goats, highlighting the role of persistent low-grade viral replication in macrophages driving chronic inflammatory lesions.
Narayan et al. (1985) studied this question.
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