Population
Excised cross-circulated dog hearts (n=11)
Comparison
Decreased coronary perfusion pressure and… vs Control (normal coronary perfusion pressure)
Design
Preclinical
Authors
Loading...
Animal data on hypoperfusion versus propranolol effects on myocardial energetics require confirmation; leaves open translation to human HF.
Decreased coronary perfusion and propranolol have different effects on the VO2-PVA relationship in dog hearts, likely due to differences in coronary O2 supply-demand balance.
Suga et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: