Why the study?
Does central application of ANG II increase fetal swallowing activity and c-fos expression in near-term ovine fetuses?
Population
Chronically prepared near-term ovine fetuses (130 +/- 2 days)
Design
Preclinical
Follow-up
3.5 hours
Authors
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Central ANG II may regulate fetal fluid balance in sheep; leaves open human translation and amniotic fluid therapies.
Does central application of ANG II increase fetal swallowing activity and c-fos expression in near-term ovine fetuses?
Central ANG II mechanisms are intact before birth and likely contribute to fetal body fluid and amniotic fluid regulation by stimulating swallowing.
Xu et al. (2001) studied this question.
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