May 1, 1968Archives of Internal Medicine

Lidocaine in Cardiac Arrhythmias

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Why the study?

Does intravenous lidocaine suppress or terminate cardiac arrhythmias in unanesthetized patients?

Population

60 unanesthetized patients with 74 cardiac arrhythmias, including patients with acute myocardial infarction…

Design

Case_series

Follow-up

Up to 5 days

Authors

JGJames I. GrossmanKaiser Foundation Hospital

Discussion

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Implication

Lidocaine may selectively suppress ventricular arrhythmias; leaves open confirmation in randomized trials of unanesthetized patients.

Structured PICO

Does intravenous lidocaine suppress or terminate cardiac arrhythmias in unanesthetized patients?

Population

60 unanesthetized patients with 74 cardiac arrhythmias (33 patients with ventricular arrhythmias, 41 patients with supraventricular arrhythmias), including patients with acute myocardial infarction and varying digitalis status.

Intervention

Intravenous lidocaine (average dose 1.5 mg/kg over 30 seconds), with a subset of 18 patients receiving continuous infusion (1 to 3.5 mg/min) for up to 5 days.

Outcome

Suppression or termination of cardiac arrhythmiassurrogate

Intravenous lidocaine is highly effective and safe for suppressing ventricular arrhythmias but is largely ineffective for supraventricular arrhythmias.

Cite This Study

James I. Grossman (1968) studied this question.

synapsesocial.com/papers/6a87f52f434ab3afbc76e744 https://doi.org/10.1001/archinte.1968.03640050006002

Topics

Atrial fibrillation Persistent AF management

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Lidocaine in Cardiac Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Lidocaine in Cardiac Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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