May 1, 2012Circulation
Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes
Why the study?
Does incomplete coronary revascularization increase the risk of major adverse cardiac events in patients with acute coronary syndromes after percutaneous coronary intervention?
Population
2954 patients with acute coronary syndromes who underwent percutaneous coronary intervention
Comparison
Incomplete coronary revascularization remaining… vs Complete revascularization (absence of ICR)
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
ICR after PCI in ACS was associated with higher 1-year MACE; extends observational data but leaves causal benefit of complete revascularization open.
Structured PICO
Does incomplete coronary revascularization increase the risk of major adverse cardiac events in patients with acute coronary syndromes after percutaneous coronary intervention?
P
Population
2954 patients with acute coronary syndromes who underwent percutaneous coronary intervention (from the ACUITY trial)
I
Intervention
Incomplete coronary revascularization (ICR) remaining after PCI, defined by diameter stenosis cutoffs ranging from ≥30% to ≥70% with reference vessel diameter ≥2.0 mm
C
Comparator
Complete revascularization (absence of ICR)
O
Outcome
1-year composite rate of major adverse cardiac events (death, myocardial infarction, or ischemia-driven unplanned revascularization)composite
Incomplete coronary revascularization after PCI in acute coronary syndromes is strongly associated with an increased 1-year risk of myocardial infarction and ischemia-driven unplanned revascularization.
Cite This Study
Rosner et al. (2012) studied this question.