Why the study?
Does growth hormone supplementation improve LV function in a porcine model of pacing-induced congestive heart failure?
Population
Pigs (n=28 total: 10 pacing CHF, 10 pacing CHF + GH, 8 controls)
Comparison
Growth hormone supplementation (200 microg x kg… vs Untreated pacing CHF and unpaced controls
Design
Preclinical
Follow-up
3 weeks
Authors
Loading...
Supports GH effects on LV function in porcine CHF models; leaves open clinical translation pending human trials.
Does growth hormone supplementation improve LV function in a porcine model of pacing-induced congestive heart failure?
Short-term growth hormone supplementation improves LV pump function and remodeling in a porcine model of pacing-induced congestive heart failure.
Houck et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: