Population
Troponin C and troponin proteins (in vitro biochemical model)
Design
Preclinical
Authors
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Informs troponin C kinetic models in cardiac muscle; leaves open in vivo relevance to relaxation rates.
The study details the calcium and magnesium binding kinetics of troponin C, suggesting that the dissociation rate of Ca2+ from high-affinity sites may be too slow to explain muscle relaxation rates.
Yasuo Ogawa (1985) studied this question.
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