What question did this study set out to answer?

To determine whether enhanced external counterpulsation improves exercise tolerance in chronic stable angina through enhanced myocardial perfusion, altered exercise hemodynamics, or both.

November 19, 2008Cardiology

Improved Exercise Tolerance following Enhanced External Counterpulsation: Cardiac or Peripheral Effect?

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Why the study?

Does enhanced external counterpulsation improve exercise hemodynamics and myocardial stress perfusion in patients with chronic stable angina?

Population

27 patients with chronic stable angina

Design

Cohort

Authors

WLWilliam E. LawsonVA Tennessee Valley Healthcare System JHJohn C.K. HuiNanfang Hospital ZZZhen Sheng Zheng81th Hospital of PLA

Discussion

Member takes

Implication

EECP was associated with improved tolerance and perfusion in stable angina; hypothesis-generating and requires RCTs before practice change.

Key Points

To determine whether enhanced external counterpulsation improves exercise tolerance in chronic stable angina through enhanced myocardial perfusion, altered exercise hemodynamics, or both.
Evaluated 27 patients with chronic stable angina undergoing enhanced external counterpulsation (EECP) therapy.
Assessed exercise tolerance, radionuclide stress myocardial perfusion images, and hemodynamic responses (heart rate and blood pressure) before and after treatment.
Exercise tolerance improved in 81% of patients (22/27) and radionuclide stress perfusion images improved in 78% of patients (21/27) following EECP.
Post-EECP maximal exercise heart rate and blood pressure maintained a linear relation with exercise duration but did not increase significantly despite longer exercise times.

Structured PICO

Does enhanced external counterpulsation improve exercise hemodynamics and myocardial stress perfusion in patients with chronic stable angina?

Population

27 patients with chronic stable angina

Intervention

Enhanced external counterpulsation (EECP)

Outcome

Exercise hemodynamics and myocardial stress perfusion (exercise tolerance and radionuclide stress perfusion images)surrogate

EECP improves exercise tolerance in patients with chronic stable angina through both improved myocardial perfusion and decreased cardiac workload.

Cite This Study

Lawson et al. (2008) studied this question.

synapsesocial.com/papers/6a87fbbd3fe66a1452bbf17c https://doi.org/10.1159/000177103

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Implication

EECP was associated with improved tolerance and perfusion in stable angina; hypothesis-generating and requires RCTs before practice change.

Improved Exercise Tolerance following Enhanced External Counterpulsation: Cardiac or Peripheral Effect?

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Improved Exercise Tolerance following Enhanced External Counterpulsation: Cardiac or Peripheral Effect?

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider