Why the study?
Does routine platelet testing improve outcomes in patients undergoing neurovascular procedures?
Does routine platelet testing improve outcomes in patients undergoing neurovascular procedures?
Despite the risks of hemorrhage and thromboembolism associated with clopidogrel response variability, routine platelet testing is not currently recommended for neurointerventional procedures.
In the context of neurointerventional procedures, clopidogrel hyper-responsiveness has been associated with hemorrhage; on the other hand, clopidogrel resistance has been associated with thromboembolism. This might seem to make a compelling argument in favor of routine platelet testing. Our reading of the literature leads us to conclude that routine platelet testing in neurointerventional procedures is not, unfortunately, ready for prime time.
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Comin et al. (2012) studied this question.
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