Why the study?
Earlier studies suggested adding acetazolamide could increase loop diuretic effectiveness in acute heart failure patients with volume excess.
Does acetazolamide added to loop diuretics improve decongestion in patients with acute heart failure?
Does acetazolamide added to loop diuretics improve decongestion in patients with acute heart failure?
Adding acetazolamide to loop diuretics in acute heart failure improves decongestion, natriuresis, and urine output, though it may increase serum creatinine.
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Supports adjunctive acetazolamide for decongestion in acute HF; extends trial data via systematic synthesis.
Fadilla et al. (2023) studied this question.
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