Why the study?
Does aspirin 81 mg daily affect mean platelet volume in healthy volunteers?
Does aspirin 81 mg daily affect mean platelet volume in healthy volunteers?
When standardized, mean platelet volume is a reproducible marker of platelet size that is not affected by low-dose aspirin.
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MPV is reproducible and aspirin-independent when standardized; supports biomarker reliability but leaves clinical validation open.
Shah et al. (2013) studied this question.
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