Why the study?
Does intravenous acepromazine alter echocardiographic measurements in healthy thoroughbred horses?
Does intravenous acepromazine alter echocardiographic measurements in healthy thoroughbred horses?
Acepromazine sedation in horses significantly alters specific echocardiographic dimensions, which must be accounted for during veterinary cardiac assessments.
Acepromazine alters specific echocardiographic dimensions in healthy horses; leaves open effects in diseased animals or clinical practice.
Eight normal thoroughbred horses were examined by echocardiography before and 10 minutes after they had been sedated by the intravenous administration of 0.03 mg/kg acepromazine. There were significant (P<0.025) increases in the diameters of the pulmonary artery and the aorta, measured at end-systole, and in the thickness of the interventricular septum, measured at end-systole and end-diastole. In addition, there was a significant (P<0.001) decrease in the diameter of the left atrium measured at end-diastole. The remaining cardiac dimensions, all the indices of cardiac function, and the occurrence and severity of valvular regurgitation were not affected by sedation.
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Nicola J. Menzies‐Gow (2008) studied this question.
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