Why the study?
Does a family history of type 2 diabetes increase the intima-media thickness of the common carotid artery in glucose-tolerant young adults?
Population
401 individuals aged 18-45 years with normal glucose tolerance (NGT)
Comparison
First-degree family history of type 2 diabetes… vs No family history of type 2 diabetes until the…
Design
Cross-sectional
Authors
Loading...
Supports early atherosclerosis signal in normoglycemic adults with diabetic family history; leaves open prospective validation before any practice change.
Does a family history of type 2 diabetes increase the intima-media thickness of the common carotid artery in glucose-tolerant young adults?
A genetic predisposition to type 2 diabetes is associated with increased carotid intima-media thickness in young adults with normal glucose tolerance, suggesting accelerated atherosclerosis.
Pannacciulli et al. (2003) studied this question.