Key result
Roux-en-Y gastric bypass yielded significantly higher total weight loss than sleeve gastrectomy (p<0.05), with 44.1% of all patients achieving ≥20% total weight loss at 2 years.
Why the study?
Bariatric surgery is a cornerstone intervention offering substantial and sustainable weight loss for individuals with severe obesity.
Does metabolic bariatric surgery (SG or RYGB) improve weight loss outcomes in patients with obesity and Type 2 diabetes?
Population
186 patients with obesity and Type 2 diabetes
Comparison
Sleeve gastrectomy vs Roux-en-Y gastric bypass
Design
Retrospective cohort study
Authors
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Supports meaningful 2-year weight loss after bariatric surgery in T2D; leaves open RYGB vs SG superiority pending randomized confirmation.
Cohort (n=186)
No
Does metabolic bariatric surgery (SG or RYGB) improve weight loss outcomes in patients with obesity and Type 2 diabetes?
p-value: p=<0.05
Metabolic bariatric surgery provides substantial and sustainable weight loss in patients with obesity and Type 2 diabetes, with RYGB yielding higher total weight loss than SG.
Leyaro et al. (2024) conducted a cohort in Obesity and Type 2 diabetes (n=186). Roux-en-Y gastric bypass (RYGB) vs. Sleeve gastrectomy (SG) was evaluated on Optimal clinical response weight loss (excess weight loss ≥50% or total weight loss ≥20%) (p=<0.05). Roux-en-Y gastric bypass yielded significantly higher total weight loss than sleeve gastrectomy (p<0.05), with 44.1% of all patients achieving ≥20% total weight loss at 2 years.
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