Key result
Sleeve gastrectomy and Roux-en-Y gastric bypass resulted in significantly greater 5-year total weight loss (16.0% and 21.7%, respectively) compared to nonsurgical treatment (2.2%).
Why the study?
Although bariatric procedures lead to substantial weight loss, few studies have compared surgical outcomes to nonsurgical treatment, particularly for sleeve gastrectomy.
Do sleeve gastrectomy and Roux-en-Y gastric bypass improve weight loss in adult patients with severe obesity compared to nonsurgical treatment?
Population
13,900 SG, 17,258 RYGB, and 87,965 matched nonsurgical adult patients with BMI ≥35 kg/m2
Comparison
SG vs RYGB vs nonsurgical treatment
Design
Retrospective matched cohort study
Follow-up
5 years (SG, RYGB, nonsurgical) and 10 years (RYGB, nonsurgical)
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RYGB and SG were associated with greater 5-year weight loss than nonsurgical care; extends observational data but leaves randomized confirmation open.
Cohort (n=119,123)
Do sleeve gastrectomy and Roux-en-Y gastric bypass improve weight loss in adult patients with severe obesity compared to nonsurgical treatment?
Absolute Event Rate: 21.7% vs 2.2%
Bariatric surgery (RYGB and SG) results in substantial and sustained weight loss at 5 to 10 years compared to nonsurgical management in patients with severe obesity.
A 2020 study conducted a cohort in Severe obesity (n=119,123). Sleeve gastrectomy and Roux-en-Y gastric bypass vs. Nonsurgical treatment was evaluated on Percent total weight loss (%TWL) at 5 years. Sleeve gastrectomy and Roux-en-Y gastric bypass resulted in significantly greater 5-year total weight loss (16.0% and 21.7%, respectively) compared to nonsurgical treatment (2.2%).
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