Key result
Robotic BPD-DS is linked to ~25% total bodyweight loss at 5 years, surpassing robotic RYGB.
Why the study?
Does rBPD-DS improve long-term weight loss compared to rRYGB in patients with insufficient weight loss or weight regain after sleeve gastrectomy?
Cohort (n=148)
Yes
Does rBPD-DS improve long-term weight loss compared to rRYGB in patients with insufficient weight loss or weight regain after sleeve gastrectomy?
In patients requiring revisional surgery after sleeve gastrectomy, rBPD-DS provides significantly greater weight loss at 5 years compared to rRYGB, though with a trend toward higher early morbidity.
Answers are grounded in this paper and cite their sources.
rBPD-DS was associated with greater 5-year weight loss after sleeve failure; leaves open optimal revisional choice pending randomized data.
Background Sleeve gastrectomy (SG) is the most performed bariatric procedure worldwide, yet the reported rate of surgical conversions due to insufficient weight loss (IWL) or weight regain (WR) is 10-20%. Aims The aim of this study was to determine the best metabolic response after robotic SG conversions for IWL/WR and identify the most appropriate surgical option. Methods We analysed prospective registry data from eight expert centres across three continents. Included patients underwent either secondary robotic Roux-en-Y gastric bypass (rRYGB) or robotic biliopancreatic diversion with duodenal switch (rBPD-DS) for IWL/WR after SG. Perioperative outcomes, postoperative morbidity assessed using the Comprehensive Complication Index (CCI®), total bodyweight loss (TBWL), and SFBARI scores were compared at 90 days, 1 year and 5 years. Results 148 patients were included; 79·7% were females, with a mean (SD) age of 44·0 (10·1) years and baseline BMI of 45·2 (8·4) kg/m². 55 (37·2%) underwent rRYGB and 93 (62·8%) rBPD-DS. Baseline characteristics were comparable. Median hospital stay was 2 days in both groups (p=0·84). An uneventful 90-day postoperative course occurred in 92·7% of patients undergoing rRYGB and 82·8% undergoing rBPD-DS (p=0·088). At 1 year, follow-up was available for 79·1% of patients; TBWL did not differ between groups (17·7% for rRYGB vs 19·2% for rBPD-DS; p=0·36), nor did SFBARI scores (33·9 vs 36·1; p=0·52). At 5 years, follow-up was available for 53·4% of patients; rBPD-DS was associated with greater TBWL (25·3% vs 14·1%; p=0·003) and higher SFBARI scores (45·1 vs 24·6; p=0·006). Conclusion As a secondary procedure for IWL/WR after SG, rBPD–DS was associated with a 9.9% higher 90-day morbidity compared to rRYGB. At 5-year follow-up, rBPD–DS was associated with significantly greater weight loss and higher SFBARI scores, suggesting a potential long-term advantage over rRYGB.
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Bartoletti et al. (2026) conducted a cohort in Insufficient weight loss or weight regain after sleeve gastrectomy (n=148). Robotic biliopancreatic diversion with duodenal switch (rBPD-DS) vs. Robotic Roux-en-Y gastric bypass (rRYGB) was evaluated on Total bodyweight loss (TBWL) at 5 years (p=0.003). Robotic biliopancreatic diversion with duodenal switch was associated with greater 5-year total bodyweight loss than robotic Roux-en-Y gastric bypass (25.3% vs 14.1%; p=0.003).
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