Stewart-Treves syndrome is a rare and highly fatal complication of chronic lymphedema, with rapid progression to pulmonary metastases and death despite treatment.
Underscores rapid fatality in Stewart-Treves syndrome; leaves open optimal management strategies for this rare entity.
Malignant tumors of the vascular endothelium complicating lymphedema (Stewart- Treves syndrome) are very rare events. A 72-year-old woman and a 52-year-old man developed angiosarcoma of the right and left lower extremity, respectively, after long standing lymphedema. The first patient had pulmonary metastases and was initially treated with chemotherapy with no response. She died of her disease 5 weeks after the biopsy. The second patient underwent disarticulation of the left leg. Four months later he developed pulmonary metastases and died.
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Papavassiliou et al. (2000) studied this question.
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