Key result
A 3-year-old female renal transplant recipient with enterovirus necrotizing myositis had complete resolution of symptoms with steroids, IVIG, reduced tacrolimus, and physical therapy.
Why the study?
Enteroviruses can cause severe infections including viral myocarditis, meningitis, acute flaccid myelitis, and viral myositis.
Case Report (n=1)
No
Enterovirus myositis should be included in the differential diagnosis for necrotizing myositis following renal transplantation in children.
Answers are grounded in this paper and cite their sources.
Enterovirus myositis merits inclusion in the differential for necrotizing myositis after pediatric renal transplant; this single case leaves optimal therapy open.
BACKGROUND: Enteroviruses can cause severe infections, including viral myocarditis, meningitis, acute flaccid myelitis, and viral myositis. METHODS/RESULTS: We report a 3-year-old female renal transplant recipient who presented to a tertiary care hospital with elevated serum liver aminotransferases and subsequently developed proximal muscle pain, weakness, and respiratory distress during the first week of hospitalization. Imaging of the lower extremities revealed diffuse myositis of the proximal thigh and pelvic muscles. A muscle biopsy was obtained and revealed necrotizing myositis with immunostaining positive for enterovirus, consistent with a diagnosis of enterovirus necrotizing myositis. She had complete resolution of symptoms with steroids, intravenous immune globulin, reduced tacrolimus dose, and physical therapy. CONCLUSIONS: Enterovirus myositis should be included in the differential diagnosis for necrotizing myositis following renal transplantation in children.
No takes yet. Share an insight, caveat, or question.
Deray et al. (2022) conducted a case report in Necrotizing enterovirus myositis (n=1). Steroids, intravenous immune globulin, reduced tacrolimus dose, and physical therapy was evaluated on Resolution of symptoms. A 3-year-old female renal transplant recipient with enterovirus necrotizing myositis had complete resolution of symptoms with steroids, IVIG, reduced tacrolimus, and physical therapy.
Synapse has enriched 10 related papers. Consider them for comparative context: