Key result
Wide surgical excision of dermatofibrosarcoma protuberans resulted in no local recurrences or metastatic activity over a 3 to 7 year follow-up period in two patients.
Case Report (n=2)
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Surgical excision with clear margins is the effective treatment for dermatofibrosarcoma protuberans to prevent local recurrence.
Dermatofibrosarcoma protuberans (DFSP) is a rare nosological entity from the group of soft tissue sarcomas. The etiology of the disease remains unclear. The neoplasm may start growing de novo over healthy skin or as a result of a local chronic trauma, radiation therapy or thermal scar. It affects more commonly middle aged patients with a clear male prevalence. Once developed, the tumor progresses slowly with an indolent growth pattern and might be wrongly taken as a benign neoplasm. However, DFSP has a high local recurrence level and intermediate metastatic activity reported. Surgical excision of the tumor is the most effective treatment method. In the following we present clinical case reports of patients with DFSP.
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Stanimirov et al. (2019) conducted a case report in Dermatofibrosarcoma protuberans (n=2). Surgical excision was evaluated on Local recurrence or metastasis. Wide surgical excision of dermatofibrosarcoma protuberans resulted in no local recurrences or metastatic activity over a 3 to 7 year follow-up period in two patients.
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