Why the study?
Is intrapulmonary production of RANTES increased during rejection and CMV pneumonitis after lung transplantation?
Population
61 lung transplant patients, including those with CMV pneumonitis, allograft rejection, and without…
Comparison
Measurement of RANTES concentration in… vs Lung transplant patients without complications
Design
Cohort
Authors
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May mark post-transplant lung complications; hypothesis-generating for RANTES as biomarker or target.
Is intrapulmonary production of RANTES increased during rejection and CMV pneumonitis after lung transplantation?
Intrapulmonary production of the chemokine RANTES by activated macrophages is increased during complications of lung transplantation, suggesting a role in immune cell recruitment.
Monti et al. (1996) studied this question.
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