Key result
Parvovirus B19 (25.0%) and non-polio enteroviruses (18%) were the most prevalent viral etiologies in myocarditis across 75 studies, whereas influenza virus accounted for only 2.0%.
Why the study?
The study was conducted to investigate the prevalence of viral myocarditis worldwide.
Meta-Analysis
Parvovirus B19 and non-polio enteroviruses are the most prevalent viral causes of myocarditis globally, highlighting the need for targeted etiologic diagnosis.
Answers are grounded in this paper and cite their sources.
Supports targeted viral testing for parvovirus B19 and enteroviruses in myocarditis; extends prior observations to global meta-analytic prevalence estimates.
Objective: To investigate the prevalence of viral myocarditis worldwide.Methods: We conducted a systematic search for the prevalence of the most common viruses in myocarditis and 75 studies were included for statistical analysis of the prevalence of adenovirus, hepatitis C virus, cytomegalovirus, Ebola virus, human herpesvirus 6, influenza virus, parvovirus, and non-polio enteroviruses.Results: The highest prevalence was related to B19 (25.0%) and non-polio enteroviruses (18%). The prevalence of human herpesvirus 6, cytomegalovirus, and Ebola virus was12.8%, 5.5%, and 3.1%, respectively. Hepatitis C virus accounted for 6.1% of the disease, the adenoviruses contributed to 5.2% of viral myocarditis. The lowest incidence was related to the influenza virus with 2.0%.Conclusions: Treatment of myocarditis is still problematic and may depend on the etiologic diagnosis. So it is important to know the commonly occurring viral factors in myocarditis and timely diagnosis and treatment are also imperative.
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Faghihloo et al. (2020) conducted a meta-analysis in Viral myocarditis. Viral etiologies (adenovirus, HCV, CMV, Ebola, HHV-6, influenza, parvovirus, non-polio enteroviruses) was evaluated on Prevalence of viral etiologies in myocarditis. Parvovirus B19 (25.0%) and non-polio enteroviruses (18%) were the most prevalent viral etiologies in myocarditis across 75 studies, whereas influenza virus accounted for only 2.0%.
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