What question did this study set out to answer?

To identify and investigate an ongoing Salmonella Enteritidis outbreak prospectively using routine whole genome sequencing and trace its transmission source through supply chain network analysis.

October 26, 2016Epidemiology and InfectionOpen Access

Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak ofSalmonellaEnteritidis

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Authors

TIThomas InnsUK Health Security Agency PAPhilip AshtonUniversity of Liverpool JLJonathan LighthillFood Standards Agency

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Implication

Genomic surveillance reveals a multi-country Salmonella Enteritidis outbreak in humans, indicating contaminated chicken eggs as a shared cross-border source.

Key Points

To identify and investigate an ongoing Salmonella Enteritidis outbreak prospectively using routine whole genome sequencing and trace its transmission source through supply chain network analysis.
Analyzed clinical isolates in England and Wales using routine whole genome sequencing to detect single nucleotide polymorphism clusters.
Interviewed UK cases regarding food histories and mapped the commercial chicken egg distribution chain.
Tested food and environmental samples from linked premises and evaluated the association between the egg food chain network and bacterial phylogeny.
Identified 136 cases in the United Kingdom and 18 cases in Spain within the single nucleotide polymorphism-defined outbreak cluster.
Demonstrated a statistically significant association between the chicken egg supply network of UK cases and the phylogeny of outbreak isolates.
Isolated an outbreak-cluster strain from an egg-containing food sample, confirming chicken eggs as the common exposure source across both countries.

Cite This Study

Inns et al. (2016) studied this question.

synapsesocial.com/papers/6a882f738c7e900eb714c4f5 https://doi.org/10.1017/s0950268816001941

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Implication

Genomic surveillance reveals a multi-country Salmonella Enteritidis outbreak in humans, indicating contaminated chicken eggs as a shared cross-border source.

Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak ofSalmonellaEnteritidis

Discussion

Member takes

Implication

Key Points

Cite This Study

Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak ofSalmonellaEnteritidis

Discussion

Member takes

Implication

Key Points

Cite This Study

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