Key result
Coronary sinus ethanol infusion eliminates refractory epicardial VT with zero recurrences through 12 months.
Why the study?
Epicardial ablation of scar-related LV VT may be required, but epicardial access can be difficult due to adhesions, antithrombotic therapies, extreme obesity, or bleeding risks.
Case Report (n=1)
No
Ethanol infusion to a coronary sinus branch may serve as an effective alternative ablation strategy for scar-related epicardial ventricular tachycardia when direct epicardial access is difficult.
Answers are grounded in this paper and cite their sources.
May offer an alternative for epicardial VT when direct access fails; leaves open efficacy and safety in larger cohorts.
Radiofrequency catheter ablation of scar-related ventricular tachycardia (VT) has been widely performed as a definitive therapy in patients with structural heart disease.1,2 An epicardial approach may sometimes be required to eliminate epicardial reentrant circuits on the left ventricular (LV) free wall. However, epicardial access can be difficult owing to pericardial adhesions, anticoagulation and/or antiplatelet therapies, extreme obesity, or the risk of bleeding complications based on anatomical backgrounds.
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Sasaki et al. (2020) conducted a case report in Scar-related ventricular tachycardia with left ventricular epicardial reentrant circuit and nonischemic cardiomyopathy (n=1). Retrograde coronary venous ethanol ablation into the posterolateral coronary sinus branch was evaluated on Elimination of sustained ventricular tachycardia and freedom from recurrence. Ethanol infusion into a posterolateral coronary sinus branch successfully eliminated scar-related epicardial ventricular tachycardia with 0 recurrences over 12 months of follow-up.
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