Key result
Visceral fat volume was significantly correlated with abdominal aorta atherosclerosis, with mean calcium scores increasing from 136.8 to 212.2 au across increasing visceral-to-subcutaneous fat ratios.
Why the study?
Does visceral fat volume correlate with abdominal aortic atherosclerosis in subjects undergoing abdominal CT?
Observational (n=424)
No
Does visceral fat volume correlate with abdominal aortic atherosclerosis in subjects undergoing abdominal CT?
Visceral fat volume, but not subcutaneous fat volume, is significantly correlated with abdominal aortic atherosclerosis as measured by CT calcium scoring.
Visceral fat may mark higher aortic atherosclerosis risk on routine CT; leaves open causality and requires prospective validation before any clinical use.
OBJECTIVE: The present study investigated effect of subcutaneous fat volume and abdominal visceral fat volume on aortic atherosclerosis via multislice computed tomography. MATERIALS AND METHODS: The present study comprised 424 subjects who underwent non-contrast-enhanced abdominal CT in our clinic between June 2012 and June 2013. Using dedicated software visceral fat volume was calculated for each individual and then subcutaneous fat volume was calculated by subtracting visceral fat volume from total fat volume. By dividing visceral fat volume/subcutaneous fat volume participants were assigned to three groups according to their mean visceral fat volume/subcutaneous fat volume: Group 1 consisted of subjects with visceral fat volume/subcutaneous fat volume lower than 0.48 (Group 1 < 0.48); Group 2 consisted of subjects with visceral fat volume/subcutaneous fat volume equal to or higher than 0.48 and lower than 0.69 (0.48 ≤ Group 2 < 0.69); and Group 3 consisted of subjects with visceral fat volume/subcutaneous fat volume equal to or higher than 0.69 (Group 3 ≥ 0.69). RESULTS: The mean abdominal aortic calcium scores according to Agatston scoring (au) were 136.8 ± 418.7 au in Group 1, 179.9 ± 463 au in Group 2 and 212.2 ± 486.9 in Group 3, respectively. CONCLUSIONS: We have demonstrated a significant correlation between visceral fat volume and abdominal aorta atherosclerosis, while there was absence of significant correlation between subcutaneous fat volume and abdominal atherosclerosis.
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Efe et al. (2014) conducted an observational in Aortic atherosclerosis (n=424). Visceral fat volume and visceral-to-subcutaneous fat ratio vs. Lower visceral-to-subcutaneous fat ratio was evaluated on Abdominal aortic calcium score (Agatston scoring). Visceral fat volume was significantly correlated with abdominal aorta atherosclerosis, with mean calcium scores increasing from 136.8 to 212.2 au across increasing visceral-to-subcutaneous fat ratios.
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