Why the study?
Does the titer of autoantibodies to β1-adrenergic receptors correlate with systolic myocardial dysfunction in elderly patients with ischemic heart disease?
Cross-Sectional (n=98)
No
Does the titer of autoantibodies to β1-adrenergic receptors correlate with systolic myocardial dysfunction in elderly patients with ischemic heart disease?
Odds Ratio: 4.2 (95% CI 2.6–6.4)
p-value: p=<0.005
Elevated titers of autoantibodies to β1-adrenergic receptors are significantly associated with systolic myocardial dysfunction in elderly patients with ischemic heart disease.
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Zharynova et al. (2014) conducted a cross-sectional in Ischemic heart disease and chronic heart failure (n=98). Elevated autoantibodies to β1-adrenergic receptors vs. Normal autoantibodies to β1-adrenergic receptors was evaluated on Systolic myocardial dysfunction (LVEF < 45%) (OR 4.2, 95% CI 2.6-6.4, p=<0.005).
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