Key result
Worsening NYHA class correlates with a ~30% lower anaerobic threshold on CPET.
Population
99 normal subjects and 382 patients with cardiac disease
Design
Cross-sectional
Authors
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May support %AT for grading HF severity; leaves open its incremental prognostic value in prospective cohorts.
Observational (n=481)
Anaerobic threshold derived from cardiopulmonary exercise testing is an objective and reliable parameter for evaluating the severity of heart failure.
Fumiaki Marumo (1989) conducted an observational in Heart failure (n=481). Anaerobic threshold (AT) and related parameters vs. Normal subjects or lower NYHA class was evaluated on Anaerobic threshold (%AT) across NYHA classes. Anaerobic threshold (%AT) determined by cardio-pulmonary exercise testing decreased progressively with worsening heart failure severity, from 90.2% in NYHA class I to 59.7% in NYHA class III.
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