Key result
Exercise intensity based on 6MWD positively correlates with anaerobic threshold in chronic heart failure.
Why the study?
To investigate the relationship between aerobic exercise intensity determined by 6MWD and anaerobic threshold in chronic heart failure patients to explore suitable exercise rehabilitation approaches.
Does exercise intensity based on 6-minute walking distance correlate with anaerobic threshold in patients with chronic heart failure?
Observational
Does exercise intensity based on 6-minute walking distance correlate with anaerobic threshold in patients with chronic heart failure?
Exercise intensity derived from the 6-minute walk test correlates positively with the anaerobic threshold from cardiopulmonary exercise testing, providing a feasible alternative for prescribing aerobic exercise in heart failure patients.
Answers are grounded in this paper and cite their sources.
Supports 6MWD-derived intensity as feasible surrogate in CHF; hypothesis-generating and requires RCT validation before practice change.
BACKGROUND: The study aimed to investigate the relationship between the aerobic exercise intensity determined by 6-minute walking distance (6MWD) and its counterpart based on anaerobic threshold (AT) in chronic heart failure (CHF) individuals for exploring suitable means for CHF exercise rehabilitation. METHODS: We retrospectively analyzed data in patient with CHF, who performed cardiopulmonary exercise test (CPET) and 6-minute walking test (6MWT) uniformly. Anthropometric characteristics, left ventricular ejection fraction (LVEF), and multiple parameters of 6MWT and AT were collected. RESULTS: The results of the analysis revealed that the 6MWD was correlated with the AT positively [CHF group: r=0.433, heart failure with reduced ejection fraction (HFrEF) group: r=0.395, heart failure with intermediate ejection fraction (HFmEF) group: r=0.477, heart failure with preserved ejection fraction (HFpEF) group: r=0.445; all P<0.05]. The regression analysis showed that the linear equation model developed can predict exercise intensity based on AT (EIAT) by exercise intensity based on 6MWD (EI6MWD), the aerobic exercise intensity based on AT and 6MWD respectively, of CHF patients. CONCLUSIONS: There is a correlation between EI6MWD and EIAT. 74.6-87.4% of EI6MWD in patients with CHF is equivalent to EIAT. It is feasible to establish the aerobic exercise intensity of patients with CHF equivalent to AT based on 6MWD.
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Luo et al. (2020) conducted an observational in Chronic heart failure. Exercise intensity based on 6-minute walking distance (EI6MWD) vs. Exercise intensity based on anaerobic threshold (EIAT) was evaluated on Correlation between 6-minute walking distance and anaerobic threshold (r=0.433, p=<0.05). Exercise intensity based on 6-minute walking distance was positively correlated with anaerobic threshold in patients with chronic heart failure (r=0.433, P<0.05).
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