Describes a case of total cardiac denervation in a diabetic patient, resulting in a fixed heart rate similar to that of a transplanted heart.
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Fixed heart rate may signal complete denervation in advanced diabetic neuropathy; leaves open mechanisms and need for prospective autonomic studies.
Total loss of the autonomic regulation of heart rate is described in a 28-year-old diabetic with extensive autonomic neuropathy. The patient had an almost fixed heart rate that barely responded to any of the tests that stimulate or inhibit the autonomic nerves. Its behavior was similar to that of the transplanted heart.
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Lloyd‐Mostyn et al. (1976) studied this question.
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