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February 25, 2009IUBMB LifeOpen Access

Na+ transport in cardiac myocytes; Implications for excitation‐contraction coupling

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Key result

Na+ transport pathways, including Na+ channels, Na+/Ca2+ exchanger, and Na+/K+ pump, play a central role in regulating intracellular Ca2+ and contractility in cardiac myocytes.

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Authors

DBDonald M. BersSDSanda Despa

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Overview

This review summarizes the critical role of intracellular Na+ concentration and its transport pathways in regulating cardiac excitation-contraction coupling.

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Cite This Study

Bers et al. (2009) reported a review. Na+ transport pathways, including Na+ channels, Na+/Ca2+ exchanger, and Na+/K+ pump, play a central role in regulating intracellular Ca2+ and contractility in cardiac myocytes.

synapsesocial.com/papers/6a884d8d7b78edf2e3609236https://doi.org/10.1002/iub.163
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