Key result
Minor stroke was associated with a higher risk of stroke or death compared to TIA over a mean observation time of 34 months (P<0.05).
Why the study?
Does a history of TIA versus minor stroke predict the risk of stroke or death?
RCT (n=101)
Mentioned
No
Does a history of TIA versus minor stroke predict the risk of stroke or death?
p-value: p=<0.05
Patients with minor stroke have a higher risk of subsequent stroke or death compared to those with TIA, which may be driven by higher rates of hypertension.
May warrant closer surveillance after minor stroke than TIA; leaves open whether intensified prevention modifies long-term outcomes.
In the Swedish aspirin low dose trial (SALT) 101 patients were enrolled from the Department of Medicine, Falun. 42 patients had experienced TIA/amaurosis fugax, whereas 59 patients had suffered a minor stroke/retinal infarction. History of hypertension treated or known untreated occurred statistically more frequently in the minor stroke group at randomisation (P less than 0.01) and the mean diastolic blood pressure (DBP) was higher in the minor stroke group during the observation time (P less than 0.05; ANOVA). The minor stroke group had less favourable outcomes according to survival curves (stroke or death) during a mean observation time of 34 months in each group (P less than 0.05 at 29 months). The findings of the present trial suggest that hypertension and the higher mean DBP during the observation time might explain the better outcome of end points of stroke or death in patients with TIA.
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Sven‐Erik Eriksson (2009) conducted an RCT in TIA or minor stroke (n=101). Minor stroke/retinal infarction vs. TIA/amaurosis fugax was evaluated on stroke or death (p=<0.05). Minor stroke was associated with a higher risk of stroke or death compared to TIA over a mean observation time of 34 months (P<0.05).
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