February 19, 2008European Journal of Echocardiography
Immediate impact of successful percutaneous mitral valve commissurotomy on right ventricular function
Why the study?
Does percutaneous mitral commissurotomy improve right ventricular function in patients with isolated rheumatic mitral stenosis?
Population
12 female patients (mean age 29 +/- 7 years) with isolated rheumatic mitral stenosis, all in sinus rhythm
Comparison
Percutaneous mitral commissurotomy (PTMC) vs Baseline (before PTMC)
Design
Cohort
Follow-up
24-48 hours
Authors
Discussion
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Member takes
Implication
Post-PTMC RV index changes may reflect acute loading rather than function; leaves open whether commissurotomy improves RV performance long-term.
Structured PICO
Does percutaneous mitral commissurotomy improve right ventricular function in patients with isolated rheumatic mitral stenosis?
P
Population
12 female patients (mean age 29 +/- 7 years) with isolated rheumatic mitral stenosis, all in sinus rhythm
I
Intervention
Percutaneous mitral commissurotomy (PTMC)
C
Comparator
Baseline (before PTMC)
O
Outcome
Global and longitudinal right ventricular function assessed by conventional and tissue Doppler imaging echocardiography at 24-48 hours after PTMCsurrogate
Successful percutaneous mitral commissurotomy yields discordant immediate effects on echocardiographic parameters of right ventricular function, likely reflecting the sensitivity of these indices to acute changes in loading conditions.
Limitations
- Small number of patients
- Relative insensitivity of currently available echocardiography parameters of RV function that are not completely immune to loading conditions
Cite This Study
Drighil et al. (2008) studied this question.