Key result
Leg elevation in coronary artery disease patients increased mitral and tricuspid peak E and A velocities; tricuspid A velocity increase correlated with positive exercise stress tests (p=0.01).
Why the study?
Does a preload increase via leg elevation alter ventricular filling dynamics in patients with coronary artery disease?
Observational (n=50)
Does a preload increase via leg elevation alter ventricular filling dynamics in patients with coronary artery disease?
Answers are grounded in this paper and cite their sources.
Leg elevation acutely alters echocardiographic parameters of ventricular filling in patients with coronary artery disease, with specific changes correlating with prior myocardial infarction and exercise stress test positivity.
This study was conducted to investigate the effects of a preload increase on ventricular filling dynamics in 50 coronary artery disease patients both before and immediately after leg elevation. Mitral and tricuspid peak E and A velocities and the mitral E/A velocity ratio increased after leg elevation whereas isovolumic relaxation time and mitral deceleration time decreased. The increase in tricuspid peak A velocity after leg elevation was related to the positivity of the exercise stress test (p = 0.01). The increase in mitral peak A velocity was related to the history of old myocardial infarction (p = 0.006).
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Kyriakides et al. (2008) conducted an observational in Coronary artery disease (n=50). Leg elevation vs. Before leg elevation was evaluated on Ventricular filling dynamics. Leg elevation in coronary artery disease patients increased mitral and tricuspid peak E and A velocities; tricuspid A velocity increase correlated with positive exercise stress tests (p=0.01).
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