Key result
Mitral balloon valvuloplasty in children with rheumatic mitral stenosis demonstrated long-term restenosis rates comparable to adults (26% vs. 31%, P=0.41) over a mean follow-up of 8.5 years.
Why the study?
Does mitral balloon valvuloplasty provide similar long-term efficacy and safety in children compared to adults with rheumatic mitral stenosis?
Cohort (n=531)
Does mitral balloon valvuloplasty provide similar long-term efficacy and safety in children compared to adults with rheumatic mitral stenosis?
Absolute Event Rate: 26% vs 31%
p-value: p=0.41
Mitral balloon valvuloplasty for rheumatic mitral stenosis is safe and effective in children, yielding better immediate hemodynamic results and comparable long-term event-free survival compared to adults.
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Supports mitral balloon valvuloplasty in children with rheumatic mitral stenosis; extends adult data but remains hypothesis-generating pending randomized trials.
Fawzy et al. (2008) conducted a cohort in Rheumatic mitral stenosis (n=531). Mitral balloon valvuloplasty in children vs. Mitral balloon valvuloplasty in adults was evaluated on Restenosis (p=0.41). Mitral balloon valvuloplasty in children with rheumatic mitral stenosis demonstrated long-term restenosis rates comparable to adults (26% vs. 31%, P=0.41) over a mean follow-up of 8.5 years.
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