Why the study?
Does injection of anterior pituitary extracts increase acetone bodies in susceptible animals?
Population
Normal fasting rats, dogs, guinea pigs, and man (susceptible animals)
Design
Preclinical
Authors
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Anterior pituitary extracts induce ketosis in animals; leaves open any role in human metabolic disease.
Does injection of anterior pituitary extracts increase acetone bodies in susceptible animals?
Anterior pituitary extracts demonstrate ketogenic activity by increasing acetone bodies in various species.
Shipley et al. (1938) studied this question.