Population
Guinea-pig cardiac muscle/cardiomyocytes, human embryonic kidney cells, and Xenopus oocytes.
Comparison
Cloning and expression of guinea-pig Kir2… vs Native inward rectifier K+ channels in…
Design
Preclinical
Authors
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No direct clinical implications yet; leaves open translation of gpKir2.x findings to human IK1 and arrhythmia mechanisms.
This study identifies the specific molecular correlates (gpKir2.1, gpKir2.2, gpKir2.3) of the native inward rectifier K+ channels in guinea-pig cardiomyocytes.
Liu et al. (2001) studied this question.
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