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March 30, 2006European Journal of Cardiovascular Prevention & Rehabilitation

Preterm delivery of a first child and subsequent mothers’ risk of ischaemic heart disease: a nested case–control study

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Why the study?

Does preterm delivery of a first child increase the risk of subsequent ischaemic heart disease in mothers?

Population

504 mothers from the E3N cohort (109 cases of ischaemic heart disease and 395 controls)

Comparison

Preterm delivery of a first child vs Mothers without preterm delivery of a first child

Design

Case-control

Authors

ONOlivier NardiMZMahmoud ZureikDCDominique Courbon

Discussion

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Member takes

Overview

May inform maternal IHD risk assessment after preterm delivery; leaves open causal inference and need for prospective validation.

Structured PICO

Does preterm delivery of a first child increase the risk of subsequent ischaemic heart disease in mothers?

P
Population
504 mothers from the E3N cohort (109 cases of ischaemic heart disease and 395 controls)
I
Intervention
Preterm delivery of a first child
C
Comparator
Mothers without preterm delivery of a first child
O
Outcome
Ischaemic heart disease (IHD)hard clinical

Preterm delivery of a first child is associated with a twofold increased risk of subsequent ischaemic heart disease in mothers, independent of major cardiovascular risk factors.

Cite This Study

Nardi et al. (2006) studied this question.

synapsesocial.com/papers/6a8856d426735dbc5f76fca6https://doi.org/10.1097/01.hjr.0000183917.35978.a6
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