What question did this study set out to answer?

To determine whether ergometrine provocation during oesophageal manometry can identify oesophageal spasm in patients presenting with angina-like chest pain and normal cardiovascular findings.

February 1, 1982GutOpen Access

Diagnosis of oesophageal spasm by ergometrine provocation.

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Authors

HDHuw DaviesJohn Innes Centre MKMichael KayeUniversity of Chicago JRJ. RhodesUniversity of Siena

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Implication

Clinical evaluation reveals ergometrine-induced motility changes and chest pain in patients with normal coronary tests, suggesting its diagnostic utility for oesophageal spasm.

Key Points

To determine whether ergometrine provocation during oesophageal manometry can identify oesophageal spasm in patients presenting with angina-like chest pain and normal cardiovascular findings.
Assessed 42 patients presenting with angina-like chest pain despite normal cardiovascular investigations.
Included 10 age-matched control subjects and 6 volunteers with coronary artery stenosis and exercise-induced angina.
Administered ergometrine provocation during oesophageal manometry to measure changes in motility and monitor reproduction of typical pain symptoms.
Ergometrine provocation induced significant deterioration in oesophageal motility alongside familiar pain in 24 of 42 non-cardiac chest pain patients.
Motility changes occurred in 4 of 10 controls (with 2 experiencing pain), whereas 0 of 6 volunteers with coronary artery stenosis developed motility abnormalities during exercise-induced angina.

Cite This Study

Davies et al. (1982) studied this question.

synapsesocial.com/papers/6a88585cceefe68dba4fcdbe https://doi.org/10.1136/gut.23.2.89

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Implication

Clinical evaluation reveals ergometrine-induced motility changes and chest pain in patients with normal coronary tests, suggesting its diagnostic utility for oesophageal spasm.

Diagnosis of oesophageal spasm by ergometrine provocation.

Discussion

Member takes

Implication

Key Points

Cite This Study

Diagnosis of oesophageal spasm by ergometrine provocation.

Discussion

Member takes

Implication

Key Points

Cite This Study

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