Key Points
- To evaluate the coronary artery pathology in Prinzmetal's variant angina pectoris and assess the role of early angiographic diagnosis and surgical bypass therapy.
- Evaluated clinical and angiographic characteristics across a case series of three patients with variant angina pectoris (N=3).
- Conducted a literature review on the clinical prognosis and pathological mechanisms of Prinzmetal's variant angina.
- Angiographic evaluation revealed single major coronary artery obstructive lesions in two of the three patients.
- Review of clinical outcomes and existing literature indicated a grave overall prognosis for patients with variant angina pectoris.
- Early angiography is recommended to detect surgically correctable obstructive lesions amenable to saphenous vein coronary artery bypass.
Structured PICO
PPopulation3 cases of Prinzmetal's variant angina pectoris
Variant angina pectoris may be associated with surgically correctable single major coronary artery obstructive lesions, suggesting a role for early angiographic evaluation.
Limitations
- Pathophysiology of this syndrome is unclarified
- Associated risks and the results to be expected from surgical therapy are unknown