BIOSYNTHESIS OF INDOLE 137 methionine and the synthesis of methionine by cell suspensions of E8ch. coli (Wijesundera & Woods, 1953; Cohn, Cohen & Monod, 1953). However, the addition of indole to the growth medium stimulated rather than depressed indole synthesis, therefore the effect of tryptophan remains unexplained. SUMMARY 1. Indole is formed from glucose and ammonium salts by washed-cell suspensions of a mutant strain of E8cherichia coli (strain 7-4) unable to convert indole into tryptophan.
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Neuberger et al. (1956) studied this question.
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