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November 16, 2018JAMA Network OpenOpen Access

Effect of Real-time Patient-Centered Education Bundle on Administration of Venous Thromboembolism Prevention in Hospitalized Patients

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Key result

A real-time, targeted, patient-centered education bundle significantly reduced the nonadministration of VTE prophylaxis in hospitalized patients (OR 0.57; 95% CI 0.48-0.67; P<0.001 for interaction).

Why the study?

Many prescribed doses of venous thromboembolism prophylaxis are not administered to hospitalized patients, primarily owing to patient refusal.

Does a real-time patient-centered education bundle reduce nonadministration of VTE prophylaxis in hospitalized patients?

Population

19 652 patient visits where at least 1 dose of VTE prophylaxis was prescribed across 16 hospital units

Comparison

Patient-centered education bundle after a missed dose vs no intervention

Design

Nonrandomized controlled preintervention-postintervention comparison trial

Authors

EHElliott R. HautJAJonathan AboagyeDSDauryne L. Shaffer

Discussion

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Member takes

Overview

May support education bundles to reduce VTE nonadministration; leaves open need for RCTs to confirm benefit.

Structured PICO

Does a real-time patient-centered education bundle reduce nonadministration of VTE prophylaxis in hospitalized patients?

P
Population
19,652 patient visits of hospitalized adults (mean age 55.6 years) prescribed at least 1 dose of VTE prophylaxis at a single center.
I
Intervention
Real-time, targeted, patient-centered education bundle delivered if a dose of VTE prophylaxis medication was not administered (implemented on 4 intervention units).
C
Comparator
No intervention (implemented on 12 control units).
O
Outcome
Conditional odds of nonadministration of doses of VTE prophylaxis before and after the intervention on control vs intervention units.

Main Result

Odds Ratio: 0.57 (95% CI 0.48–0.67)

Absolute Event Rate: 5.6% vs 13.3%

p-value: p=<0.001

A targeted, real-time patient-centered education bundle significantly reduces the nonadministration of pharmacologic VTE prophylaxis in hospitalized patients.

Cite This Study

Haut et al. (2018) studied Venous thromboembolism prophylaxis (n=19,652). Real-time, targeted, patient-centered education bundle vs. No intervention (control units) was evaluated on Conditional odds of nonadministration of doses of VTE prophylaxis (OR 0.57, 95% CI 0.48-0.67, p=<0.001). A real-time, targeted, patient-centered education bundle significantly reduced the nonadministration of VTE prophylaxis in hospitalized patients (OR 0.57; 95% CI 0.48-0.67; P<0.001 for interaction).

synapsesocial.com/papers/6a886360ecbb6f2effa53d14https://doi.org/10.1001/jamanetworkopen.2018.4741
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