Why the study?
Does controlled respiration cause cyclic fluctuations in atrial fibrillatory frequency in patients with chronic atrial fibrillation and complete heart block?
Does controlled respiration cause cyclic fluctuations in atrial fibrillatory frequency in patients with chronic atrial fibrillation and complete heart block?
Controlled respiration causes cyclic fluctuations in atrial fibrillatory frequency in patients with long-duration AF, a phenomenon attenuated by vagal blockade, suggesting parasympathetic modulation of the atrial refractory period.
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Supports vagal modulation of atrial frequency in chronic AF; hypothesis-generating for autonomic therapies and should not yet change practice.
Holmqvist et al. (2005) studied this question.
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