Why the study?
Can a Bayes theorem approach combining clinical and laboratory data provide an evidence-based diagnosis of type 1 von Willebrand disease?
Population
Patients evaluated for type 1 von Willebrand disease
Design
Other
Authors
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Supports probabilistic type 1 VWD diagnosis; hypothesis-generating and requires prospective validation before practice change.
Can a Bayes theorem approach combining clinical and laboratory data provide an evidence-based diagnosis of type 1 von Willebrand disease?
A Bayesian approach combining bleeding score, VWF levels, and family history provides an evidence-based method for defining minimal criteria to diagnose type 1 von Willebrand disease.
Tosetto et al. (2008) studied this question.
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