Population
Patients evaluated for or diagnosed with Von Willebrand disease type 1
Design
Review
Authors
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Questions VWD type 1 diagnostic criteria; leaves open whether risk-based models should supplant binary thresholds.
The diagnosis of VWD type 1 may be flawed due to the continuous nature of VWF levels, suggesting a need for an empirical epidemiologic risk management approach rather than binary disease categorization.
J. Evan Sadler (2003) studied this question.
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